Synthesis, Molecular Docking Analysis and Biological Evaluations of Saccharide-Modified Thiadiazole Sulfonamide Derivatives

A series of saccharide-modified thiadiazole sulfonamide derivatives has been designed and synthesized by the “tail approach” and evaluated for inhibitory activity against carbonic anhydrases II, IX, and XII. Most of the compounds showed high topological polar surface area (TPSA) values and excellent...

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Detalles Bibliográficos
Autores principales: Zhang, Zuo-Peng, Zhong, Ye, Han, Zhen-Bin, Zhou, Lin, Su, Hua-Sheng, Wang, Jian, Liu, Yang, Cheng, Mao-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196973/
https://www.ncbi.nlm.nih.gov/pubmed/34067452
http://dx.doi.org/10.3390/ijms22115482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196973/
https://www.ncbi.nlm.nih.gov/pubmed/34067452
http://dx.doi.org/10.3390/ijms22115482

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