Molecular Mechanisms of PD-1 and PD-L1 Activity on a Pan-Cancer Basis: A Bioinformatic Exploratory Study

Immune checkpoint blockade targeting PD-1 (PDCD1)/PD-L1 (CD274) is increasingly used for multiple cancers. However, efficacy and adverse-related events vary significantly. This bioinformatic study interrogated molecular differences pertaining to PDCD1/CD274 and their correlated genes on a pan-cancer...

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Detalles Bibliográficos
Autores principales: Kannan, Siddarth, O’Connor, Geraldine Martina, Bakker, Emyr Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196980/
https://www.ncbi.nlm.nih.gov/pubmed/34067485
http://dx.doi.org/10.3390/ijms22115478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196980/
https://www.ncbi.nlm.nih.gov/pubmed/34067485
http://dx.doi.org/10.3390/ijms22115478

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