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Global Chromatin Changes Resulting from Single-Gene Inactivation—The Role of SMARCB1 in Malignant Rhabdoid Tumor

SIMPLE SUMMARY: Malignant rhabdoid tumors (MRT), one of the most lethal, treatment-resistant human cancers, arises in young children within brain, kidney, liver and/or soft tissues. Generally, cancer arises in older adults, and results from multiple significant changes (mutations) accumulating in th...

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Detalles Bibliográficos
Autores principales: Kenny, Colin, O’Meara, Elaine, Ulaş, Mevlüt, Hokamp, Karsten, O’Sullivan, Maureen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197137/
https://www.ncbi.nlm.nih.gov/pubmed/34071089
http://dx.doi.org/10.3390/cancers13112561