Mathematical Modelling Based on In Vivo Imaging Suggests CD137-Stimulated Cytotoxic T Lymphocytes Exert Superior Tumour Control Due to an Enhanced Antimitotic Effect on Tumour Cells

SIMPLE SUMMARY: Cytotoxic T lymphocytes (CTLs) play an important role in controlling tumours, and an improved understanding of how they accomplish this will benefit immunotherapeutic cancer treatment strategies. Stimulation of CTLs by targeting their CD137 receptor is a strategy currently under inve...

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Detalles Bibliográficos
Autores principales: Beck, Richard J., Weigelin, Bettina, Beltman, Joost B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197176/
https://www.ncbi.nlm.nih.gov/pubmed/34073822
http://dx.doi.org/10.3390/cancers13112567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197176/
https://www.ncbi.nlm.nih.gov/pubmed/34073822
http://dx.doi.org/10.3390/cancers13112567

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