P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice

Non-alcoholic fatty liver disease (NAFLD) is a chronic metabolic liver disease associated with obesity and insulin resistance. Activation of the purinergic receptor P2Y2R has been reported to promote adipogenesis, inflammation and dyslipidemia in adipose tissues in obese mice. However, the role of P...

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Detalles Bibliográficos
Autores principales: Dusabimana, Theodomir, Park, Eun Jung, Je, Jihyun, Jeong, Kyuho, Yun, Seung Pil, Kim, Hye Jung, Kim, Hwajin, Park, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197197/
https://www.ncbi.nlm.nih.gov/pubmed/34073834
http://dx.doi.org/10.3390/ijms22115528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197197/
https://www.ncbi.nlm.nih.gov/pubmed/34073834
http://dx.doi.org/10.3390/ijms22115528

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