High-Throughput Sequencing of Phage Display Libraries Reveals Parasitic Enrichment of Indel Mutants Caused by Amplification Bias

The combination of phage display technology with high-throughput sequencing enables in-depth analysis of library diversity and selection-driven dynamics. We applied short-read sequencing of the mutagenized region on focused display libraries of two homologous nucleic acid modification eraser protein...

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Detalles Bibliográficos
Autores principales: Plessers, Sander, Van Deuren, Vincent, Lavigne, Rob, Robben, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197208/
https://www.ncbi.nlm.nih.gov/pubmed/34073702
http://dx.doi.org/10.3390/ijms22115513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197208/
https://www.ncbi.nlm.nih.gov/pubmed/34073702
http://dx.doi.org/10.3390/ijms22115513

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