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8a, a New Acridine Antiproliferative and Pro-Apoptotic Agent Targeting HDAC1/DNMT1

Epigenetic therapy using histone deacetylase (HDAC) inhibitors has become an attractive project in new drug development. However, DNA methylation and histone acetylation are important epigenetic ways to regulate the occurrence and development of leukemia. Given previous studies, N-(2-aminophenyl)ben...

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Detalles Bibliográficos
Autores principales: Zhang, Qiting, Wang, Ziyan, Chen, Xinyuan, Qiu, Haoxiang, Gu, Yifan, Wang, Ning, Wang, Tao, Wang, Ze, Ma, Huabin, Zhao, Yufen, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197214/
https://www.ncbi.nlm.nih.gov/pubmed/34073721
http://dx.doi.org/10.3390/ijms22115516