Both Specific Endothelial and Proximal Tubular Adam17 Deletion Protect against Diabetic Nephropathy

ADAM17 is a disintegrin and metalloproteinase capable of cleaving the ectodomains of a diverse variety of molecules including TNF-α, TGF-α, L-selectin, and ACE2. We have previously demonstrated that renal ADAM17 is upregulated in diabetic mice. The role of endothelial (eAdam17) and proximal tubular...

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Detalles Bibliográficos
Autores principales: Palau, Vanesa, Nugraha, Bramasta, Benito, David, Pascual, Julio, Emmert, Maximilian Y., Hoerstrup, Simon P., Riera, Marta, Soler, Maria José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197223/
https://www.ncbi.nlm.nih.gov/pubmed/34073747
http://dx.doi.org/10.3390/ijms22115520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197223/
https://www.ncbi.nlm.nih.gov/pubmed/34073747
http://dx.doi.org/10.3390/ijms22115520

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