The DEAD/DEAH Box Helicase, DDX11, Is Essential for the Survival of Advanced Clear Cell Renal Cell Carcinoma and Is a Determinant of PARP Inhibitor Sensitivity

SIMPLE SUMMARY: DDX11, a helicase involved in sister chromatid cohesion, was identified as a significant biomarker of aggressive renal cell carcinoma (RCC) in our previous studies. In this study, we evaluated the molecular pathways through which DDX11 is involved in RCC cell survival. Furthermore, w...

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Detalles Bibliográficos
Autores principales: Park, Jee Soo, Lee, Myung Eun, Jang, Won Sik, Rha, Koon Ho, Lee, Seung Hwan, Lee, Jongsoo, Ham, Won Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197413/
https://www.ncbi.nlm.nih.gov/pubmed/34073906
http://dx.doi.org/10.3390/cancers13112574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197413/
https://www.ncbi.nlm.nih.gov/pubmed/34073906
http://dx.doi.org/10.3390/cancers13112574

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