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The DEAD/DEAH Box Helicase, DDX11, Is Essential for the Survival of Advanced Clear Cell Renal Cell Carcinoma and Is a Determinant of PARP Inhibitor Sensitivity
SIMPLE SUMMARY: DDX11, a helicase involved in sister chromatid cohesion, was identified as a significant biomarker of aggressive renal cell carcinoma (RCC) in our previous studies. In this study, we evaluated the molecular pathways through which DDX11 is involved in RCC cell survival. Furthermore, w...
Autores principales: | Park, Jee Soo, Lee, Myung Eun, Jang, Won Sik, Rha, Koon Ho, Lee, Seung Hwan, Lee, Jongsoo, Ham, Won Sik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197413/ https://www.ncbi.nlm.nih.gov/pubmed/34073906 http://dx.doi.org/10.3390/cancers13112574 |
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