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Liquid–liquid phase separation of tau: From molecular biophysics to physiology and disease

Biomolecular condensation via liquid–liquid phase separation (LLPS) of intrinsically disordered proteins/regions (IDPs/IDRs), with and without nucleic acids, has drawn widespread interest due to the rapidly unfolding role of phase‐separated condensates in a diverse range of cellular functions and hu...

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Detalles Bibliográficos
Autores principales: Rai, Sandeep K., Savastano, Adriana, Singh, Priyanka, Mukhopadhyay, Samrat, Zweckstetter, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197432/
https://www.ncbi.nlm.nih.gov/pubmed/33930220
http://dx.doi.org/10.1002/pro.4093