Defucosylation of Tumor-Specific Humanized Anti-MUC1 Monoclonal Antibody Enhances NK Cell-Mediated Anti-Tumor Cell Cytotoxicity

SIMPLE SUMMARY: Antibodies with their high specificity to antigens have been widely used in cancer immunotherapy. Natural killer (NK) cells are a group of innate immune cells which have strong cytotoxicity against cancerous cells, virus infected cells, or transformed cells. NK cells express abundant...

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Detalles Bibliográficos
Autores principales: Gong, Ying, Klein Wolterink, Roel G. J., Gulaia, Valeriia, Cloosen, Silvie, Ehlers, Femke A. I., Wieten, Lotte, Graus, Yvo F., Bos, Gerard M. J., Germeraad, Wilfred T. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197514/
https://www.ncbi.nlm.nih.gov/pubmed/34070311
http://dx.doi.org/10.3390/cancers13112579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197514/
https://www.ncbi.nlm.nih.gov/pubmed/34070311
http://dx.doi.org/10.3390/cancers13112579

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