Ubiquitin-Specific Protease 3 Deubiquitinates and Stabilizes Oct4 Protein in Human Embryonic Stem Cells

Oct4 is an important mammalian POU family transcription factor expressed by early human embryonic stem cells (hESCs). The precise level of Oct4 governs the pluripotency and fate determination of hESCs. Several post-translational modifications (PTMs) of Oct4 including phosphorylation, ubiquitination,...

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Detalles Bibliográficos
Autores principales: Rhie, Byung-Ho, Antao, Ainsley Mike, Karapurkar, Janardhan Keshav, Kim, Min-Seong, Jo, Won-Jun, Ramakrishna, Suresh, Kim, Kye-Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197518/
https://www.ncbi.nlm.nih.gov/pubmed/34070420
http://dx.doi.org/10.3390/ijms22115584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197518/
https://www.ncbi.nlm.nih.gov/pubmed/34070420
http://dx.doi.org/10.3390/ijms22115584

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