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Folate Receptor Beta as a Direct and Indirect Target for Antibody-Based Cancer Immunotherapy

Folate receptor beta (FRβ) is a folate binding receptor expressed on myeloid lineage hematopoietic cells. FRβ is commonly expressed at high levels on malignant blasts in patients with acute myeloid leukemia (AML), as well as on M2 polarized tumor-associated macrophages (TAMs) in the tumor microenvir...

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Detalles Bibliográficos
Autores principales: Roy, Allison G., Robinson, J. Michael, Sharma, Prannda, Rodriguez-Garcia, Alba, Poussin, Mathilde A., Nickerson-Nutter, Cheryl, Powell, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197521/
https://www.ncbi.nlm.nih.gov/pubmed/34070369
http://dx.doi.org/10.3390/ijms22115572