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Folate Receptor Beta as a Direct and Indirect Target for Antibody-Based Cancer Immunotherapy
Folate receptor beta (FRβ) is a folate binding receptor expressed on myeloid lineage hematopoietic cells. FRβ is commonly expressed at high levels on malignant blasts in patients with acute myeloid leukemia (AML), as well as on M2 polarized tumor-associated macrophages (TAMs) in the tumor microenvir...
Autores principales: | Roy, Allison G., Robinson, J. Michael, Sharma, Prannda, Rodriguez-Garcia, Alba, Poussin, Mathilde A., Nickerson-Nutter, Cheryl, Powell, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197521/ https://www.ncbi.nlm.nih.gov/pubmed/34070369 http://dx.doi.org/10.3390/ijms22115572 |
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