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The association of DAT gene methylation with striatal DAT availability in healthy subjects

BACKGROUND: DNA methylation inhibits gene expression by preventing transcription factors from binding to DNA. Functioning of nigrostriatal dopaminergic neurons is influenced by the expression of the dopamine transporter (DAT), and genetic variations in the gene encoding DAT contribute to differences...

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Detalles Bibliográficos
Autores principales: Pak, Kyoungjune, Seok, Ju Won, Nam, Hyun-Yeol, Seo, Seongho, Lee, Myung Jun, Kim, Keunyoung, Kim, In Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197693/
https://www.ncbi.nlm.nih.gov/pubmed/34120227
http://dx.doi.org/10.1186/s13550-021-00800-y