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Forcing dividing cancer cells to die; low‐dose drug combinations to prevent spindle pole clustering
Mitosis, under the control of the microtubule-based mitotic spindle, is an attractive target for anti-cancer treatments, as cancer cells undergo frequent and uncontrolled cell divisions. Microtubule targeting agents that disrupt mitosis or single molecule inhibitors of mitotic kinases or microtubule...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197716/ https://www.ncbi.nlm.nih.gov/pubmed/33870441 http://dx.doi.org/10.1007/s10495-021-01671-3 |