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Forcing dividing cancer cells to die; low‐dose drug combinations to prevent spindle pole clustering

Mitosis, under the control of the microtubule-based mitotic spindle, is an attractive target for anti-cancer treatments, as cancer cells undergo frequent and uncontrolled cell divisions. Microtubule targeting agents that disrupt mitosis or single molecule inhibitors of mitotic kinases or microtubule...

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Detalles Bibliográficos
Autores principales: Ducrey, Eloise, Castrogiovanni, Cédric, Meraldi, Patrick, Nowak-Sliwinska, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197716/
https://www.ncbi.nlm.nih.gov/pubmed/33870441
http://dx.doi.org/10.1007/s10495-021-01671-3