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Carcinoma-associated fibroblasts derived exosomes modulate breast cancer cell stemness through exonic circHIF1A by miR-580-5p in hypoxic stress

Hypoxia is a common phenomenon in solid tumors. The roles of exosomes from hypoxic breast cancer stroma are less studied. So, the study was aimed to investigate the role of exosomes from hypoxic cancer-associated fibroblasts (CAFs) cells in breast cancer. The circRNA array analysis was performed to...

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Detalles Bibliográficos
Autores principales: Zhan, Yanxia, Du, Junxian, Min, Zhihui, Ma, Li, Zhang, Wei, Zhu, Wei, Liu, Yonglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197761/
https://www.ncbi.nlm.nih.gov/pubmed/34120145
http://dx.doi.org/10.1038/s41420-021-00506-z