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EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance

SIMPLE SUMMARY: Growth factors are hormone-like molecules able to promote division and migration of normal cells, but cancer captured the underlying mechanisms to unleash tumor growth and metastasis. Here we review the epidermal growth factor (EGF), which controls epithelial cells, the precursors of...

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Detalles Bibliográficos
Autores principales: Uribe, Mary Luz, Marrocco, Ilaria, Yarden, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197917/
https://www.ncbi.nlm.nih.gov/pubmed/34206026
http://dx.doi.org/10.3390/cancers13112748