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Mechanisms and Regulation of Cardiac Ca(V)1.2 Trafficking

During cardiac excitation contraction coupling, the arrival of an action potential at the ventricular myocardium triggers voltage-dependent L-type Ca(2+) (Ca(V)1.2) channels in individual myocytes to open briefly. The level of this Ca(2+) influx tunes the amplitude of Ca(2+)-induced Ca(2+) release f...

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Detalles Bibliográficos
Autores principales: Westhoff, Maartje, Dixon, Rose E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197997/
https://www.ncbi.nlm.nih.gov/pubmed/34072954
http://dx.doi.org/10.3390/ijms22115927