Cargando…

Mechanisms and Regulation of Cardiac Ca(V)1.2 Trafficking

During cardiac excitation contraction coupling, the arrival of an action potential at the ventricular myocardium triggers voltage-dependent L-type Ca(2+) (Ca(V)1.2) channels in individual myocytes to open briefly. The level of this Ca(2+) influx tunes the amplitude of Ca(2+)-induced Ca(2+) release f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Westhoff, Maartje, Dixon, Rose E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197997/ https://www.ncbi.nlm.nih.gov/pubmed/34072954 http://dx.doi.org/10.3390/ijms22115927

Ejemplares similares

Acute phosphatidylinositol 4,5 bisphosphate depletion destabilizes sarcolemmal expression of cardiac L-type Ca(2+) channel Ca(V)1.2
por: Voelker, Taylor L., et al.
Publicado: (2023)

Dynamic L-type Ca(V)1.2 channel trafficking facilitates Ca(V)1.2 clustering and cooperative gating
por: Ghosh, Debapriya, et al.
Publicado: (2018)

β-Adrenergic control of sarcolemmal Ca(V)1.2 abundance by small GTPase Rab proteins
por: del Villar, Silvia G., et al.
Publicado: (2021)

Ca(V)β-subunit dependence of forward and reverse trafficking of Ca(V)1.2 calcium channels
por: Ferron, Laurent, et al.
Publicado: (2022)

Ca(2+) regulation of constitutive vesicle trafficking
por: Sargeant, John, et al.
Publicado: (2022)

Graded Ca(2+)/calmodulin-dependent coupling of voltage-gated Ca(V)1.2 channels
por: Dixon, Rose E, et al.
Publicado: (2015)

Multifaceted Roles of ALG-2 in Ca(2+)-Regulated Membrane Trafficking
por: Maki, Masatoshi, et al.
Publicado: (2016)

Rad regulation of Ca(V)1.2 channels controls cardiac fight-or-flight response
por: Papa, Arianne, et al.
Publicado: (2022)

Allicin disrupts cardiac Cav1.2 channels via trafficking
por: Han, Dan, et al.
Publicado: (2019)

Mechanism and Regulation of Nucleocytoplasmic Trafficking of Smad
por: Chen, Xiaochu, et al.
Publicado: (2011)

Ca(V)1.2 channelopathic mutations evoke diverse pathophysiological mechanisms
por: Bamgboye, Moradeke A., et al.
Publicado: (2022)

The quest to identify the mechanism underlying adrenergic regulation of cardiac Ca(2+) channels
por: Roybal, Daniel, et al.
Publicado: (2020)

NPC1-dependent alterations in K(V)2.1–Ca(V)1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease
por: Casas, Maria, et al.
Publicado: (2023)

Mechanisms controlling the trafficking, localization, and abundance of presynaptic Ca(2+) channels
por: Cunningham, Karen L., et al.
Publicado: (2023)

Mechanism of adrenergic Ca(V)1.2 stimulation revealed by proximity proteomics
por: Liu, Guoxia, et al.
Publicado: (2020)

Oxidative Regulation of Vascular Ca(v)1.2 Channels Triggers Vascular Dysfunction in Hypertension-Related Disorders
por: Hu, Xiang-Qun, et al.
Publicado: (2022)

Ca(v)1.2, Cell Proliferation, and New Target in Atherosclerosis
por: Soldatov, Nikolai M.
Publicado: (2013)

Molecular Determinants of Ca(v)1.2 Calcium Channel Inactivation
por: Soldatov, Nikolai M.
Publicado: (2012)

The role of CaMKK2 in Golgi-associated vesicle trafficking
por: Kennedy, Grace, et al.
Publicado: (2023)

PIKfyve regulates Ca(V)1.2 degradation and prevents excitotoxic cell death
por: Tsuruta, Fuminori, et al.
Publicado: (2009)

β‐adrenergic‐mediated dynamic augmentation of sarcolemmal Ca(V)1.2 clustering and co‐operativity in ventricular myocytes
por: Ito, Danica W., et al.
Publicado: (2019)

Regulation of Cardiac Cav1.2 Channels by Calmodulin
por: Kameyama, Masaki, et al.
Publicado: (2023)

Convergent regulation of Ca(V)1.2 channels by direct phosphorylation and by the small GTPase RAD in the cardiac fight-or-flight response
por: Hovey, Liam, et al.
Publicado: (2022)

The trafficking of Na(V)1.8
por: Swanwick, Richard S., et al.
Publicado: (2010)

Ca(2+) entry into neurons is facilitated by cooperative gating of clustered Ca(V)1.3 channels
por: Moreno, Claudia M, et al.
Publicado: (2016)

An epilepsy-associated K(V)1.2 charge-transfer-center mutation impairs K(V)1.2 and K(V)1.4 trafficking
por: Nilsson, Michelle, et al.
Publicado: (2022)

Increased intracellular magnesium attenuates β-adrenergic stimulation of the cardiac Ca(V)1.2 channel
por: Brunet, Sylvain, et al.
Publicado: (2013)

The role of luminal Ca regulation in Ca signaling refractoriness and cardiac arrhythmogenesis
por: Györke, Sándor, et al.
Publicado: (2017)

Ambiguous interactions between diastolic and SR Ca(2+) in the regulation of cardiac Ca(2+) release
por: Sobie, Eric A., et al.
Publicado: (2017)

K(V)11.1, Na(V)1.5, and Ca(V)1.2 Transporter Proteins as Antitarget for Drug Cardiotoxicity
por: Kowalska, Magdalena, et al.
Publicado: (2020)

Rapid Turnover of the Cardiac L-Type Ca(V)1.2 Channel by Endocytic Recycling Regulates Its Cell Surface Availability
por: Conrad, Rachel, et al.
Publicado: (2018)

Role of putative voltage-sensor countercharge D4 in regulating gating properties of Ca(V)1.2 and Ca(V)1.3 calcium channels
por: Costé de Bagneaux, Pierre, et al.
Publicado: (2018)

Remodeling of Ion Channel Trafficking and Cardiac Arrhythmias
por: Blandin, Camille E., et al.
Publicado: (2021)

Effect of Ca(v)β Subunits on Structural Organization of Ca(v)1.2 Calcium Channels
por: Kobrinsky, Evgeny, et al.
Publicado: (2009)

The CCT chaperonin is a novel regulator of Ca(2+) signaling through modulation of Orai1 trafficking
por: Hodeify, Rawad, et al.
Publicado: (2018)

Orchestrating Ca(2+) influx through Ca(V)1.2 and Ca(V)3.x channels in human cerebral arteries
por: Collier, Daniel M., et al.
Publicado: (2015)

The AKAP Cypher/Zasp contributes to β-adrenergic/PKA stimulation of cardiac Ca(V)1.2 calcium channels
por: Yu, Haijie, et al.
Publicado: (2018)

SPCA2 Regulates Orai1 Trafficking and Store Independent Ca(2+) Entry in a Model of Lactation
por: Cross, Brandie M., et al.
Publicado: (2013)

Distinct RGK GTPases Differentially Use α(1)- and Auxiliary β-Binding-Dependent Mechanisms to Inhibit Ca(V)1.2/Ca(V)2.2 Channels
por: Yang, Tingting, et al.
Publicado: (2012)

Novel insights into mechanisms for Pak1-mediated regulation of cardiac Ca(2+) homeostasis
por: Wang, Yanwen, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_klvet58k1fgt8k6ruhe5ulcg6p