Cargando…

PPARα Agonist, MHY3200, Alleviates Renal Inflammation during Aging via Regulating ROS/Akt/FoxO1 Signaling

PPARα is a ligand-dependent transcription factor and its activation is known to play an important role in cell defense through anti-inflammatory and antioxidant effects. MHY3200 (2-[4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy]-2,2-difluoroacetic acid), a novel benzothiazole-derived peroxisome proliferat...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Min Jo, Kim, Dae Hyun, Bang, EunJin, Noh, Sang Gyun, Chun, Pusoon, Yokozawa, Takako, Moon, Hyung Ryong, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198004/
https://www.ncbi.nlm.nih.gov/pubmed/34073584
http://dx.doi.org/10.3390/molecules26113197