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PPARα Agonist, MHY3200, Alleviates Renal Inflammation during Aging via Regulating ROS/Akt/FoxO1 Signaling
PPARα is a ligand-dependent transcription factor and its activation is known to play an important role in cell defense through anti-inflammatory and antioxidant effects. MHY3200 (2-[4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy]-2,2-difluoroacetic acid), a novel benzothiazole-derived peroxisome proliferat...
Autores principales: | Kim, Min Jo, Kim, Dae Hyun, Bang, EunJin, Noh, Sang Gyun, Chun, Pusoon, Yokozawa, Takako, Moon, Hyung Ryong, Chung, Hae Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198004/ https://www.ncbi.nlm.nih.gov/pubmed/34073584 http://dx.doi.org/10.3390/molecules26113197 |
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