Sialic Acid-Siglec Axis in Human Immune Regulation, Involvement in Autoimmunity and Cancer and Potential Therapeutic Treatments

Siglecs are sialic acid-binding immunoglobulin-like lectins. Most Siglecs function as transmembrane receptors mainly expressed on blood cells in a cell type-specific manner. They recognize and bind sialic acids in specific linkages on glycoproteins and glycolipids. Since Sia is a self-molecule, Sigl...

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Detalles Bibliográficos
Autores principales: Gianchecchi, Elena, Arena, Andrea, Fierabracci, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198044/
https://www.ncbi.nlm.nih.gov/pubmed/34071314
http://dx.doi.org/10.3390/ijms22115774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198044/
https://www.ncbi.nlm.nih.gov/pubmed/34071314
http://dx.doi.org/10.3390/ijms22115774

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