Treg-Resistant Cytotoxic CD4(+) T Cells Dictate T Helper Cells in Their Vicinity: TH17 Skewing and Modulation of Proliferation

Cytotoxic CD4(+) T cells (CD4 CTL) are terminally differentiated T helper cells that contribute to autoimmune diseases, such as multiple sclerosis. We developed a novel triple co-culture transwell assay to study mutual interactions between CD4 CTL, conventional TH cells, and regulatory T cells (Treg...

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Detalles Bibliográficos
Autores principales: Hoeks, Cindy, Vanheusden, Marjan, Peeters, Liesbet M., Stinissen, Piet, Broux, Bieke, Hellings, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198086/
https://www.ncbi.nlm.nih.gov/pubmed/34073458
http://dx.doi.org/10.3390/ijms22115660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198086/
https://www.ncbi.nlm.nih.gov/pubmed/34073458
http://dx.doi.org/10.3390/ijms22115660

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