Synthesis and Antitumor Activity of 1-Substituted 1,2,3-Triazole-Mollugin Derivatives

A new series of mollugin-1,2,3-triazole derivatives were synthesized using a copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition reaction of corresponding O-propargylated mollugin with aryl azides. All the compounds were evaluated for their cytotoxicity on five human cancer cell lines (HL-60, A549...

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Detalles Bibliográficos
Autores principales: Luo, Han, Lv, Yong-Feng, Zhang, Hong, Hu, Jiang-Miao, Li, Hong-Mei, Liu, Shou-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198100/
https://www.ncbi.nlm.nih.gov/pubmed/34071319
http://dx.doi.org/10.3390/molecules26113249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198100/
https://www.ncbi.nlm.nih.gov/pubmed/34071319
http://dx.doi.org/10.3390/molecules26113249

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