Deficits in Prenatal Serine Biosynthesis Underlie the Mitochondrial Dysfunction Associated with the Autism-Linked FMR1 Gene

Fifty-five to two hundred CGG repeats (called a premutation, or PM) in the 5′-UTR of the FMR1 gene are generally unstable, often expanding to a full mutation (>200) in one generation through maternal inheritance, leading to fragile X syndrome, a condition associated with autism and other intellec...

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Detalles Bibliográficos
Autores principales: Nolin, Sarah L., Napoli, Eleonora, Flores, Amanda, Hagerman, Randi J., Giulivi, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198117/
https://www.ncbi.nlm.nih.gov/pubmed/34070950
http://dx.doi.org/10.3390/ijms22115886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198117/
https://www.ncbi.nlm.nih.gov/pubmed/34070950
http://dx.doi.org/10.3390/ijms22115886

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