Inhibitory Effect of a Glutamine Antagonist on Proliferation and Migration of VSMCs via Simultaneous Attenuation of Glycolysis and Oxidative Phosphorylation

Excessive proliferation and migration of vascular smooth muscle cells (VSMCs) contribute to the development of atherosclerosis and restenosis. Glycolysis and glutaminolysis are increased in rapidly proliferating VSMCs to support their increased energy requirements and biomass production. Thus, it is...

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Detalles Bibliográficos
Autores principales: Park, Hyeon Young, Kim, Mi-Jin, Lee, Seunghyeong, Jin, Jonghwa, Lee, Sungwoo, Kim, Jung-Guk, Choi, Yeon-Kyung, Park, Keun-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198131/
https://www.ncbi.nlm.nih.gov/pubmed/34070527
http://dx.doi.org/10.3390/ijms22115602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198131/
https://www.ncbi.nlm.nih.gov/pubmed/34070527
http://dx.doi.org/10.3390/ijms22115602

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