Exercise Inhibits Doxorubicin-Induced Damage to Cardiac Vessels and Activation of Hippo/YAP-Mediated Apoptosis

SIMPLE SUMMARY: We developed a juvenile mouse cardiotoxicity model and demonstrated that doxorubicin treatment led to cardiac vascular damage involving a decrease in vascular endothelial cells and pericytes. By contrast, cardiac vessels in mice treated with exercise (Ex) during Dox treatment had no...

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Detalles Bibliográficos
Autores principales: Tao, Rong-Hua, Kobayashi, Masato, Yang, Yuanzheng, Kleinerman, Eugenie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198139/
https://www.ncbi.nlm.nih.gov/pubmed/34205942
http://dx.doi.org/10.3390/cancers13112740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198139/
https://www.ncbi.nlm.nih.gov/pubmed/34205942
http://dx.doi.org/10.3390/cancers13112740

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