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Evaluation of Substituted N-Phenylpiperazine Analogs as D3 vs. D2 Dopamine Receptor Subtype Selective Ligands

N-phenylpiperazine analogs can bind selectively to the D3 versus the D2 dopamine receptor subtype despite the fact that these two D2-like dopamine receptor subtypes exhibit substantial amino acid sequence homology. The binding for a number of these receptor subtype selective compounds was found to b...

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Detalles Bibliográficos
Autores principales: Lee, Boeun, Taylor, Michelle, Griffin, Suzy A., McInnis, Tamara, Sumien, Nathalie, Mach, Robert H., Luedtke, Robert R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198181/
https://www.ncbi.nlm.nih.gov/pubmed/34073405
http://dx.doi.org/10.3390/molecules26113182