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Genomic Characterization of Cisplatin Response Uncovers Priming of Cisplatin-Induced Genes in a Resistant Cell Line

Cisplatin is a chemotherapy drug that kills cancer cells by damaging their DNA. In human cells, this damage is repaired primarily by nucleotide excision repair. While cisplatin is generally effective, many cancers exhibit initial or acquired resistance to it. Here, we studied cisplatin resistance in...

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Detalles Bibliográficos
Autores principales: Golan Berman, Hadar, Chauhan, Pooja, Shalev, Shira, Hassanain, Hiba, Parnas, Avital, Adar, Sheera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198185/
https://www.ncbi.nlm.nih.gov/pubmed/34071702
http://dx.doi.org/10.3390/ijms22115814