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The PFKFB3 Inhibitor AZ67 Inhibits Angiogenesis Independently of Glycolysis Inhibition

Angiogenesis is the process of new blood vessel formation. In this complex orchestrated growth, many factors are included. Lately, focus has shifted to endothelial cell metabolism, particularly to the PFKFB3 protein, a key regulatory enzyme of the glycolytic pathway. A variety of inhibitors of this...

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Detalles Bibliográficos
Autores principales: Emini Veseli, Besa, Van Wielendaele, Pieter, Delibegovic, Mirela, Martinet, Wim, De Meyer, Guido R. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198190/
https://www.ncbi.nlm.nih.gov/pubmed/34073144
http://dx.doi.org/10.3390/ijms22115970