Cargando…

Dual Actions of A(2A) and A(3) Adenosine Receptor Ligand Prevents Obstruction-Induced Kidney Fibrosis in Mice

Kidney fibrosis is the final outcome of chronic kidney disease (CKD). Adenosine plays a significant role in protection against cellular damage by activating four subtypes of adenosine receptors (ARs), A(1)AR, A(2A)AR, A(2B)AR, and A(3)AR. A(2A)AR agonists protect against inflammation, and A(3)AR ant...

Descripción completa

Detalles Bibliográficos
Autores principales: Pak, Eun Seon, Jeong, Lak Shin, Hou, Xiyan, Tripathi, Sushil K., Lee, Jiyoun, Ha, Hunjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198234/
https://www.ncbi.nlm.nih.gov/pubmed/34073488
http://dx.doi.org/10.3390/ijms22115667