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Emerging Insights into Targeted Therapy-Tolerant Persister Cells in Cancer

SIMPLE SUMMARY: Acquired resistance to molecularly targeted therapies remains a major challenge in the treatment of cancer. It has been hypothesized that drug-tolerant (or “persister”) cells without bona fide resistance mechanisms may survive initial drug treatment and undergo further evolution over...

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Detalles Bibliográficos
Autores principales: Cabanos, Heidie Frisco, Hata, Aaron N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198243/
https://www.ncbi.nlm.nih.gov/pubmed/34071428
http://dx.doi.org/10.3390/cancers13112666