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Calreticulin Deficiency Disturbs Ribosome Biogenesis and Results in Retardation in Embryonic Kidney Development

Nephrogenesis is driven by complex signaling pathways that control cell growth and differentiation. The endoplasmic reticulum chaperone calreticulin (Calr) is well known for its function in calcium storage and in the folding of glycoproteins. Its role in kidney development is still not understood. W...

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Detalles Bibliográficos
Autores principales: Serin, Nazli, Dihazi, Gry H., Tayyeb, Asima, Lenz, Christof, Müller, Gerhard A., Zeisberg, Michael, Dihazi, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198291/
https://www.ncbi.nlm.nih.gov/pubmed/34070742
http://dx.doi.org/10.3390/ijms22115858