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LEDGF/p75 Is Required for an Efficient DNA Damage Response

Lens epithelium-derived growth factor splice variant of 75 kDa (LEDGF/p75) plays an important role in cancer, but its DNA-damage repair (DDR)-related implications are still not completely understood. Different LEDGF model cell lines were generated: a complete knock-out of LEDGF (KO) and re-expressio...

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Detalles Bibliográficos
Autores principales: Liedtke, Victoria, Schröder, Christian, Roggenbuck, Dirk, Weiss, Romano, Stohwasser, Ralf, Schierack, Peter, Rödiger, Stefan, Schenk, Lysann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198318/
https://www.ncbi.nlm.nih.gov/pubmed/34070855
http://dx.doi.org/10.3390/ijms22115866