The Role of Non-Specific Interactions in Canonical and ALT-Associated PML-Bodies Formation and Dynamics

In this work, we put forward a hypothesis about the decisive role of multivalent nonspecific interactions in the early stages of PML body formation. Our analysis of the PML isoform sequences showed that some of the PML isoforms, primarily PML-II, are prone to phase separation due to their polyamphol...

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Detalles Bibliográficos
Autores principales: Fonin, Alexander V., Silonov, Sergey A., Shpironok, Olesya G., Antifeeva, Iuliia A., Petukhov, Alexey V., Romanovich, Anna E., Kuznetsova, Irina M., Uversky, Vladimir N., Turoverov, Konstantin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198325/
https://www.ncbi.nlm.nih.gov/pubmed/34072343
http://dx.doi.org/10.3390/ijms22115821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198325/
https://www.ncbi.nlm.nih.gov/pubmed/34072343
http://dx.doi.org/10.3390/ijms22115821

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