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Effect and Biocompatibility of a Cross-Linked Hyaluronic Acid and Polylactide-co-glycolide Microcapsule Vehicle in Intratympanic Drug Delivery for Treating Acute Acoustic Trauma

The treatment of acute hearing loss is clinically challenging due to the low efficacy of drug delivery into the inner ear. Local intratympanic administration of dexamethasone (D) and insulin-like growth factor 1 (IGF1) has been proposed for treatment, but they do not persist in the middle ear becaus...

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Detalles Bibliográficos
Autores principales: Cho, Jung-Ah, Kim, Bong Jik, Hwang, Yu-Jung, Woo, Shin-Wook, Noh, Tae-Soo, Suh, Myung-Whan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198354/
https://www.ncbi.nlm.nih.gov/pubmed/34072013
http://dx.doi.org/10.3390/ijms22115720