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MiR-139 Modulates Cancer Stem Cell Function of Human Breast Cancer through Targeting CXCR4

SIMPLE SUMMARY: The C-X-C motif chemokine receptor 4 (CXCR4) is overexpressed in various cancer stem/progenitor cells via activation of the epithelial-mesenchymal transition (EMT) program to facilitate tumor cell aggressiveness in the premetastatic niche. Through miRNAs microarray and bioinformatics...

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Detalles Bibliográficos
Autores principales: Cheng, Chun-Wen, Liao, Wen-Ling, Chen, Po-Ming, Yu, Jyh-Cherng, Shiau, Hui-Ping, Hsieh, Yi-Hsien, Lee, Huei-Jane, Cheng, Yu-Chun, Wu, Pei-Ei, Shen, Chen-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198393/
https://www.ncbi.nlm.nih.gov/pubmed/34070538
http://dx.doi.org/10.3390/cancers13112582