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Curcumin-Loaded Nanoparticles Impair the Pro-Tumor Activity of Acid-Stressed MSC in an In Vitro Model of Osteosarcoma

In the tumor microenvironment, mesenchymal stromal cells (MSCs) are key modulators of cancer cell behavior in response to several stimuli. Intratumoral acidosis is a metabolic trait of fast-growing tumors that can induce a pro-tumorigenic phenotype in MSCs through the activation of the NF-κB-mediate...

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Detalles Bibliográficos
Autores principales: Di Pompo, Gemma, Cortini, Margherita, Palomba, Roberto, Di Francesco, Valentina, Bellotti, Elena, Decuzzi, Paolo, Baldini, Nicola, Avnet, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198446/
https://www.ncbi.nlm.nih.gov/pubmed/34071200
http://dx.doi.org/10.3390/ijms22115760