AID Contributes to Accelerated Disease Progression in the TCL1 Mouse Transplant Model for CLL

SIMPLE SUMMARY: Cancers, such as chronic lymphocytic leukemia, frequently acquire consecutive somatic mutations in the genome, which contribute to disease progression and treatment resistance. Activation-induced deaminase is an enzyme responsible for generating the highly diverse B cell repertoire b...

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Detalles Bibliográficos
Autores principales: Schubert, Maria, Gassner, Franz Josef, Huemer, Michael, Höpner, Jan Philip, Akimova, Ekaterina, Steiner, Markus, Egle, Alexander, Greil, Richard, Zaborsky, Nadja, Geisberger, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198502/
https://www.ncbi.nlm.nih.gov/pubmed/34073525
http://dx.doi.org/10.3390/cancers13112619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198502/
https://www.ncbi.nlm.nih.gov/pubmed/34073525
http://dx.doi.org/10.3390/cancers13112619

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