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Lysophosphatidic Acid Accelerates Bovine In Vitro-Produced Blastocyst Formation through the Hippo/YAP Pathway

The segregation of trophectoderm (TE) and inner cell mass in early embryos is driven primarily by the transcription factor CDX2. The signals that trigger CDX2 activation are, however, less clear. In mouse embryos, the Hippo-YAP signaling pathway is important for the activation of CDX2 expression; it...

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Detalles Bibliográficos
Autores principales: Yu, Bo, van Tol, Helena T. A., Oei, Christine H. Y., Stout, Tom A. E., Roelen, Bernard A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198578/
https://www.ncbi.nlm.nih.gov/pubmed/34072880
http://dx.doi.org/10.3390/ijms22115915