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A Computer-Based Methodology to Design Non-Standard Peptides Potentially Able to Prevent HOX-PBX1-Associated Cancer Diseases

In the last decades, HOX proteins have been extensively studied due to their pivotal role in transcriptional events. HOX proteins execute their activity by exploiting a cooperative binding to PBX proteins and DNA. Therefore, an increase or decrease in HOX activity has been associated with both solid...

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Detalles Bibliográficos
Autores principales: Gulotta, Maria Rita, De Simone, Giada, John, Justin, Perricone, Ugo, Brancale, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198631/
https://www.ncbi.nlm.nih.gov/pubmed/34073517
http://dx.doi.org/10.3390/ijms22115670