Dexamethasone Downregulates Autophagy through Accelerated Turn-Over of the Ulk-1 Complex in a Trabecular Meshwork Cells Strain: Insights on Steroid-Induced Glaucoma Pathogenesis

Steroid-induced glaucoma is a severe pathological condition, sustained by a rapidly progressive increase in intraocular pressure (IOP), which is diagnosed in a subset of subjects who adhere to a glucocorticoid (GC)-based therapy. Molecular and clinical studies suggest that either natural or syntheti...

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Detalles Bibliográficos
Autores principales: Sbardella, Diego, Tundo, Grazia Raffaella, Coletta, Massimo, Manni, Gianluca, Oddone, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198647/
https://www.ncbi.nlm.nih.gov/pubmed/34072647
http://dx.doi.org/10.3390/ijms22115891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198647/
https://www.ncbi.nlm.nih.gov/pubmed/34072647
http://dx.doi.org/10.3390/ijms22115891

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