Cargando…
Dexamethasone Downregulates Autophagy through Accelerated Turn-Over of the Ulk-1 Complex in a Trabecular Meshwork Cells Strain: Insights on Steroid-Induced Glaucoma Pathogenesis
Steroid-induced glaucoma is a severe pathological condition, sustained by a rapidly progressive increase in intraocular pressure (IOP), which is diagnosed in a subset of subjects who adhere to a glucocorticoid (GC)-based therapy. Molecular and clinical studies suggest that either natural or syntheti...
Autores principales: | Sbardella, Diego, Tundo, Grazia Raffaella, Coletta, Massimo, Manni, Gianluca, Oddone, Francesco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198647/ https://www.ncbi.nlm.nih.gov/pubmed/34072647 http://dx.doi.org/10.3390/ijms22115891 |
Ejemplares similares
-
Protein expression in human trabecular meshwork: downregulation of RhoGDI by dexamethasone in vitro
por: Yu, Minbin, et al.
Publicado: (2010) -
Citicoline Eye Drops Protect Trabecular Meshwork Cells from Oxidative Stress Injury in a 3D In Vitro Glaucoma Model
por: Vernazza, Stefania, et al.
Publicado: (2022) -
Integrins in Trabecular Meshwork and Optic Nerve Head: Possible Association with the Pathogenesis of Glaucoma
por: Zhong, Yisheng, et al.
Publicado: (2013) -
Physiological function of myocilin and its role in the pathogenesis of glaucoma in the trabecular meshwork (Review)
por: Wang, Hongwei, et al.
Publicado: (2019) -
YAP and TAZ mediate steroid-induced alterations in the trabecular meshwork cytoskeleton in human trabecular meshwork cells
por: Peng, Jie, et al.
Publicado: (2018)