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Computational-Driven Epitope Verification and Affinity Maturation of TLR4-Targeting Antibodies

Toll-like receptor (TLR) signaling plays a critical role in the induction and progression of autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematous, experimental autoimmune encephalitis, type 1 diabetes mellitus and neurodegenerative diseases. Deciphering antigen recognition b...

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Detalles Bibliográficos
Autores principales: Ahmad, Bilal, Batool, Maria, Kim, Moon-Suk, Choi, Sangdun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198660/
https://www.ncbi.nlm.nih.gov/pubmed/34206009
http://dx.doi.org/10.3390/ijms22115989