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Computational-Driven Epitope Verification and Affinity Maturation of TLR4-Targeting Antibodies
Toll-like receptor (TLR) signaling plays a critical role in the induction and progression of autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematous, experimental autoimmune encephalitis, type 1 diabetes mellitus and neurodegenerative diseases. Deciphering antigen recognition b...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198660/ https://www.ncbi.nlm.nih.gov/pubmed/34206009 http://dx.doi.org/10.3390/ijms22115989 |