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Coralyne Radiosensitizes A549 Cells by Upregulation of CDKN1A Expression to Attenuate Radiation Induced G2/M Block of the Cell Cycle

Coralyne is a synthetic analog of berberine related to protoberberine-isoquinoline alkaloids. Isoquinoline derivatives and analogs are renowned as potent radiosensitizers with potential medical application. In the present study, we investigated the effect of coralyne on the cell death, cytoskeletal...

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Detalles Bibliográficos
Autores principales: Węgierek-Ciuk, Aneta, Arabski, Michał, Ciepluch, Karol, Brzóska, Kamil, Lisowska, Halina, Czerwińska, Malwina, Stępkowski, Tomasz, Lis, Krzysztof, Lankoff, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198675/
https://www.ncbi.nlm.nih.gov/pubmed/34071406
http://dx.doi.org/10.3390/ijms22115791