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Coralyne Radiosensitizes A549 Cells by Upregulation of CDKN1A Expression to Attenuate Radiation Induced G2/M Block of the Cell Cycle
Coralyne is a synthetic analog of berberine related to protoberberine-isoquinoline alkaloids. Isoquinoline derivatives and analogs are renowned as potent radiosensitizers with potential medical application. In the present study, we investigated the effect of coralyne on the cell death, cytoskeletal...
Autores principales: | Węgierek-Ciuk, Aneta, Arabski, Michał, Ciepluch, Karol, Brzóska, Kamil, Lisowska, Halina, Czerwińska, Malwina, Stępkowski, Tomasz, Lis, Krzysztof, Lankoff, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198675/ https://www.ncbi.nlm.nih.gov/pubmed/34071406 http://dx.doi.org/10.3390/ijms22115791 |
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