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Synthesis of Novel Halogenated Heterocycles Based on o-Phenylenediamine and Their Interactions with the Catalytic Subunit of Protein Kinase CK2

Protein kinase CK2 is a highly pleiotropic protein kinase capable of phosphorylating hundreds of protein substrates. It is involved in numerous cellular functions, including cell viability, apoptosis, cell proliferation and survival, angiogenesis, or ER-stress response. As CK2 activity is found pert...

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Detalles Bibliográficos
Autores principales: Winiewska-Szajewska, Maria, Maciejewska, Agnieszka Monika, Speina, Elżbieta, Poznański, Jarosław, Paprocki, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198750/
https://www.ncbi.nlm.nih.gov/pubmed/34070615
http://dx.doi.org/10.3390/molecules26113163