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Molecular Competition in G1 Controls When Cells Simultaneously Commit to Terminally Differentiate and Exit the Cell Cycle

Terminal differentiation is essential for the development and maintenance of tissues in all multi-cellular organisms and is associated with permanent exit from the cell cycle. Failure to permanently exit the cell cycle can result in cancer and disease. However, the molecular mechanisms and timing th...

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Detalles Bibliográficos
Autores principales: Zhao, Michael L., Rabiee, Atefeh, Kovary, Kyle M., Bahrami-Nejad, Zahra, Taylor, Brooks, Teruel, Mary N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198760/
https://www.ncbi.nlm.nih.gov/pubmed/32553172
http://dx.doi.org/10.1016/j.celrep.2020.107769